Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame

Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame

Consumers are increasingly concerned about the quality and safety of many products present in the diet of industrialized countries, in particular, the use of artificial sweeteners, flavorings, colorings, preservatives, and dietary supplements. General apprehension also exists regarding the possible long-term health
effects of the raw materials and technologies used for the packaging, sterilization, and distribution of foods. Of particular concern are the potential carcinogenic effects of these products and processes.

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Aspartame induces lymphomas and leukaemias in rats

Aspartame study 14 July 2005 Eur. J. Oncol., vol. 10, n. 2, pp. 00-00, 2005

Aspartame induces lymphomas and leukaemias in rats

Summary
Aspartame, a widely used artificial sweetener, was administered with feed to male and female Sprague-Dawley rats (100-150/sex/group), 8 weeks-old at the start of the experiment, at concentrations of 100,000; 50,000; 10,000; 2,000; 400; 80 and 0 ppm.
Treatment lasted until spontaneous death of the animals. In this report we present the first results showing that aspartame, in our experimental conditions, causes a statistically significant, dose-related increase in lymphomas and leukaemias in females. No statistically significant increase in malignant brain tumours was observed among animals from the treated groups as compared to controls. Eur. J. Oncol., 10 (2), 00-00, 2005

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